Retevmo Selpercatinib 80 Mg Capsules

Description

Selpercatinib 80mg is a prescription medicine that is used to treat certain cancers caused by abnormal RET genes in adults with non-small cell lung cancer (NSCLC) that has spread, adults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread who require a medicine by mouth or injection (systemic therapy), and adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread who require a medicine by mouth or injection (systemic therapy) and who have received radioactive iodine and it did not work or is no longer working.Your healthcare provider will perform a test to make sure that Selpercatinibis right for you. It is not known if Selpercatinibis safe and effective in children younger than 12 years of age.Selpercatinibwas approved based on the percentage of patients whose tumor size shrank or disappeared after treatment and how long the response lasted. Studies are ongoing to confirm the benefit of Selpercatinibfor this use.Selpercatinibmay affect both healthy cells and tumor cells, which can result in side effects, some of which can be serious.Important Facts About RETEVMO® (reh-TEHV-moh). It is also known as selpercatinib.Selpercatinibis a prescription medicine that is used to treat certain cancers caused by an abnormal gene, called RET, in:adults with non-small cell lung cancer (NSCLC) that has spread.adults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread, who need a medicine that can be taken by mouth or injection.adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread, who need a medicine that can be taken by mouth or injection, and who have received radioactive iodine and it did not work or is no longer working.Your doctor will perform a test to make sure that Selpercatinibis right for you.It is not known if Selpercatinibis safe and effective in children younger than 12 years of age.WarningsSelpercatinibmay cause serious side effects, including:Liver problems: Liver problems (higher levels of liver enzymes) are common with Selpercatiniband may sometimes be serious. Your doctor will do blood tests before and during treatment with Selpercatinibto check for liver problems. Tell your doctor right away if you get any of the following symptoms of liver problems during treatment:yellowing of your skin or the white part of your eyes (jaundice)dark, “tea-colored” urinesleepinessbleeding or bruisingloss of appetitenausea or vomitingpain on the upper right side of your stomach areaIf you develop liver problems while taking RETEVMO, your doctor may lower your dose, stop treatment for a while, or stop treatment permanently.High blood pressure (hypertension): High blood pressure is common with Selpercatinib It may sometimes be serious. You should check your blood pressure regularly during treatment with Selpercatinib Tell your doctor if you get any of the following symptoms during treatment:confusionheadachesshortness of breathdizzinesschest painHeart rhythm changes (QT prolongation) can happen. These may be serious. Selpercatinibmay cause very slow, very fast, or irregular heartbeats. Tell your doctor right away if you get any of the following symptoms during treatment:loss of consciousnessfaintingdizzinessa change in the way your heart beats (heart palpitations)Bleeding problems: Selpercatinibcan cause bleeding, which can be serious and may lead to death.