Cometriq Cabozantinib 20mg Capsules

Description

COMETRIQ (Cabozantinib 100mg) is a prescription medicine used to treat people with medullary thyroid cancer (MTC) that has spread to other parts of the body (called metastatic MTC). It is not known if COMETRIQ is safe and effective in children. COMETRIQ may cause serious side effects, including: A tear in your stomach or intestinal wall (perforation), or an abnormal connection between 2 parts of your body (fistula) that may lead to death. Tell your healthcare provider right away if you get tenderness or pain in your stomach area (abdomen). Bleeding (hemorrhage). COMETRIQ can cause severe bleeding that may lead to death. Tell your healthcare provider right away if you get any signs of bleeding during treatment with COMETRIQ, including: coughing up blood or blood clots vomiting blood or if your vomit looks like coffee grounds red or black (looks like tar) stools menstrual bleeding that is heavier than normal any unusual or heavy bleeding Blood clots, stroke, heart attack, and chest pain. Get emergency help right away if you get: swelling or pain in your arms or legs shortness of breath light-headed or faint sweating more than usual numbness or weakness of your face, arm, or leg, especially on one side of your body sudden confusion, trouble speaking or understanding sudden trouble seeing in one or both eyes sudden trouble walking dizziness, loss of balance or coordination a sudden severe headache Wound healing problems. Wound healing problems have happened in some people who take COMETRIQ. Tell your healthcare provider if you plan to have any surgery before or during treatment with COMETRIQ. You should stop taking COMETRIQ at least 3 weeks before planned surgery. Your healthcare provider should tell you when you may start taking COMETRIQ again after surgery. High blood pressure (hypertension). Hypertension is common with COMETRIQ and can be severe. Your healthcare provider will check your blood pressure before you start and during treatment with COMETRIQ. If needed, your healthcare provider may prescribe medicine to treat your high blood pressure. Severe jaw bone problems (osteonecrosis). Symptoms may include jaw pain, toothache, or sores on your gums. Your healthcare provider should examine your mouth before you start and during treatment with COMETRIQ. Tell your dentist that you are taking COMETRIQ. It is important for you to practice good mouth care during treatment with COMETRIQ. Diarrhea. Diarrhea is common with COMETRIQ and can be severe. If needed, your healthcare provider may prescribe medicine to treat your diarrhea. Tell your healthcare provider right away if you have frequent loose, watery bowel movements. A skin problem called hand-foot skin reaction. Hand-foot skin reactions are common with COMETRIQ and can be severe. Tell your healthcare provider right away if you have rashes, redness, pain, swelling, or blisters on the palms of your hands or soles of your feet. Protein in your urine and possible kidney problems. Symptoms may include swelling in your hands, arms, legs, or feet. Reversible posterior leukoencephalopathy syndrome (RPLS). A condition called reversible posterior leukoencephalopathy syndrome can happen during treatment with COMETRIQ. Tell your healthcare provider right away if you have headaches, seizures, confusion, changes in vision, or problems thinking. Your healthcare provider may change your dose, temporarily stop, or permanently stop treatment with COMETRIQ if you have certain side effects.